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Pulmonary Disorders

The NanoNOx Inhaler Drug Delivery Platform

The NanoNOx Inhaler delivers NanoNOx as an alternative to inhaled nitric oxide gas delivery. NanoNOx offers drug Delivery & Palliative Asthma/COPD Relief, without steroids.

NanoNOx Unique Patentes Inhaler Technology.

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NanoNOx can deliver encapsulated NO as an alternative to inhaled NO gas delivery platform – Stand alone or combined with drug.

Features: 

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No heat, No Battery.

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Liquid is vaporized into nano scale droplets for inhalation.

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Liquid contains NanoNOx alone or NanoNOx with other molecule.

NanoNOx delivers effectively to the bronchial tubes in the upper lobes of the lungs because of much smaller nanoparticles unlike inhalers/nebulizers.

The NanoNOx Solution can deliver NO nanoparticles over 4-12 hours, tunable by application and molecule.

The Markets: The COPD & Asthma $39 B market and $1.243 B drug delivery market 1+2

The NanoNOx Inhaler can treat the following Disorders:

Pulmonary Hypertension

Acute Respiratory Distress Syndrom (ARDS)

Pediatric Bronchitis

Chronic obstructive Pulmonary Distress (COPD)

Systic Fibrosis

NanoNOx       Competitors:
Inhalation (Gas, Inhalers, Nebulizers) & NO Macroparticles

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NanoNOx’s Advantages: Timed Release, Dosage & Precise Delivery

Advantages of NanoNOx Inhaler

vs

NO Gas Tanks today

1.NO Tank Gas has 30-60 sec half life for

        in situ use

   vs

       NanoNOx timed release, up to 12 hours

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2.NanoNOx handheld inhaler provides portable flexibility not easily done with tanks

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Advantages of NanoNOx Inhaler

 vs

Standard Inhalers & Nebulizers

1.Only device to use NO’s vasodilator and anti-inflammatory characteristics to enhance drug absorption

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2.Competitors deliver larger macroparticles that do not reach the upper lobes well because of sizes generally are 400-600 nm

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Advantages of NanoNOx Nanoparticle

vs

L Arginine, L Citrulline, SNP, SNAP and other NO Macroparticles

1.Other NO macroparticle delivery systems lack ability to cross cell membrane with pure NO

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2.Other NOs lack stability

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3.Other NOs may lack NO dosage precision and the ability to deliver sufficient NO dosage for efficacy

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4.Other NO macroparticles require cascade of reactions before crossing cell membrane with NO

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5.NO inducing drugs cause systemic risks

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NMB THERAPEUTICS, INC. © 2020

925 - 280 -7373

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395 Westubry Blvd.

Hempstead, N.Y, 11550   

U.S.A

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